Bryan Coburn

I am a Clinician-Scientist in Infectious Diseases at the University Health Network in Toronto, where I attend on the inpatient General ID consult service (at Toronto General, Toronto Western and Mount Sinai Hospitals) and have outpatient practices in post-discharge General ID follow-up, HIV treatment and prevention, and Tuberculosis (at the TWH TB clinic). I lead an Infectious Diseases Clinical Research Unit at the UHN that undertakes human clinical trials in infectious diseases, antimicrobial stewardship, and microbiome-targeting therapies.

My lab studies human microbiomes in health and disease, including human clinical trials of microbiome-targeting therapies in infectious and non-infectious diseases. We are specifically interested in the effects of various treatments (particularly antibiotics) on the composition of the gut microbiome and microbiomes of other mucosal surfaces. Our goal is to translate our understanding of the complexity and function of the human microbiome to diagnosis, prognosis, and treatment of human diseases in which microbiome perturbation has been implicated, including sexual/reproductive health, cancer, critical illness, and the treatment and prevention of bacterial infections.

Academic appointments: Departments of Medicine (primary), Immunology, and Laboratory Medicine and Pathobiology (LMP).

Clinical appointments: University Health Network (Toronto General and Toronto Western Hospitals) and Sinai Health Systems (Mount Sinai Hospital).