Immunology

 

COVID-19, Vaccines and How They Work

View a presentation from Professor Tania Watts explaining the immunology of COVID-19 as well as information relating to the newly developed vaccines.

 

COVID-19 Infosheets

Graduate students from our department have created info sheets on the current COVID-19 pandemic that help explain some of the immunology-related issues.

 

Recent Publications From Our Department

Isho B, Abe KT, et al. 2020. Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients. Science Immunology5

Xia MH, Luo TNYX, et al. 2020. Effect of Ibrutinib on the IFN Response of Chronic Lymphocytic Leukemia Cells. Journal Of Immunology205:2629-2639

Preuss F, Chatterjee D, et al. 2020. Nucleotide Binding, Evolutionary Insights, and Interaction Partners of the Pseudokinase Unc-51-like Kinase 4. Structure28:1184

Girard M, Law JC, et al. 2020. Type I interferons drive the maturation of human DC3s with a distinct costimulatory profile characterized by high GITRL. Science Immunology5

Thai E, Costa G, et al. 2020. A high-affinity antibody against the CSP N-terminal domain lacks Plasmodium falciparum inhibitory activity. Journal Of Experimental Medicine217

Vultaggio A, Agache I, et al. 2020. Considerations on biologicals for patients with allergic disease in times of the COVID-19 pandemic: An EAACI statement. Allergy75:2764-2774

Kohno M, Murakami J, et al. 2020. Foxp3(+) Regulatory T Cell Depletion after Nonablative Oligofractionated Irradiation Boosts the Abscopal Effects in Murine Malignant Mesothelioma. Journal Of Immunology205:2519

Besaw JE, Ou WL, et al. 2020. The crystal structures of a chloride-pumping microbial rhodopsin and its proton-pumping mutant illuminate proton transfer determinants. Journal Of Biological Chemistry295:14793-14804

Kaur S, Auger C, et al. 2020. Adipose Tissue Metabolic Function and Dysfunction: Impact of Burn Injury. Frontiers In Cell And Developmental Biology8

Zhou Q, Chen V, et al. 2020. Interferon-alpha 2b Treatment for COVID-19 (vol 11, 1061, 2020). Frontiers In Immunology11

Wang A, Rojas O, et al. . Regulation of neuroinflammation by B cells and plasma cells. Immunological Reviews

Kojovic D, Ghoneim RH, et al. 2020. Role of HIV and Antiretroviral Therapy on the Expression of Placental Transporters in Women with HIV. Aaps Journal22

Rajakumar SA, Danska JS. . Bad to the bone: B cell acute lymphoblastic leukemia cells mediate bone destruction. Molecular & Cellular Oncology

Born W, Zuniga-Pflucker JC, et al. . Wendy Havran: Scientist, mentor, advocate. Immunological Reviews

Anderson MK, Selvaratnam JS. . Interaction between gamma delta TCR signaling and the E protein-Id axis in gamma delta T cell development. Immunological Reviews

Rodrigues E, Jung J, et al. 2020. A versatile soluble siglec scaffold for sensitive and quantitative detection of glycan ligands. Nature Communications11

Matsuyama T, Kubli SP, et al. . An aberrant STAT pathway is central to COVID-19. Cell Death And Differentiation

Meza-Escobar LE, Rehou S, et al. . Sepsis Definitions in Burns. Surgical Infections

Hoghooghi V, Palmer AL, et al. 2020. Cystatin C Plays a Sex-Dependent Detrimental Role in Experimental Autoimmune Encephalomyelitis. Cell Reports33

Agache I, Song Y, et al. . Efficacy and safety of dupilumab for moderate-to-severe atopic dermatitis: A systematic review for the EAACI biologicals guidelines. Allergy

Girardin SE, Cuziol C, et al. . The eIF2 alpha kinase HRI in innate immunity, proteostasis, and mitochondrial stress. Febs Journal

Abe KT, Li ZJ, et al. 2020. A simple protein-based surrogate neutralization assay for SARS-CoV-2. JCI Insight5

Sokolowska M, Lukasik ZM, et al. 2020. Immunology of COVID-19: Mechanisms, clinical outcome, diagnostics, and perspectives-A report of the European Academy of Allergy and Clinical Immunology (EAACI). Allergy75:2445-2476

Breiteneder H, Peng YQ, et al. . Biomarkers for diagnosis and prediction of therapy responses in allergic diseases and asthma. Allergy

Kent OA, Saha M, et al. 2020. Haploinsufficiency of RREB1 causes a Noonan-like RASopathy via epigenetic reprogramming of RAS-MAPK pathway genes. Nature Communications11

Rajakumar SA, Papp E, et al. 2020. B cell acute lymphoblastic leukemia cells mediate RANK-RANKL-dependent bone destruction. Science Translational Medicine12

Last Updated December 4, 2020

Dec 7 Yu Xuan Luo & Luke Neufeld
Student Seminar | 10:00am–11:00am
Dec 7 Timothy Hand, PhD
Easton Seminar | 11:00am
Dec 14 Louis Ngai & Kyle Reid
Student Seminar | 10:00am–11:00am
Dec 14 David Schatz, PhD
Easton Seminar | 11:00am
Jan 4 Julia Szusz & Derek Tsang
Student Seminar | 10:00am–11:00am

Tweets

Temerty Medicine
@uoftmedicine
Interested in nephrology and how medical treatments have been tailored to improve patient outcomes? Check out the nā€¦ https://t.co/wDz55aVUBb
Temerty Medicine
@uoftmedicine
RT : It's ! This week, we are featuring one of our PhD students "Wade Michaelchuk" šŸ‘šŸ‘šŸ‘ ---ā€¦ https://t.co/zkfZusb4zL
Temerty Medicine
@uoftmedicine
Congratulations, Arnav! We will miss you šŸ’™
IMMpress Magazine Volume 8 Number 1
IMMPress:
Climate Change & The Environment