Trinity College in the Summer

Department of Immunology

Faculty Highlight - Dr. Tak Mak's interview on Canada Files

Screenshot of Dr. Tak Mak and Interviewer

Dr. Tak Mak's interview was featured on PBS on May 7, 2024.


Higashiyama M, Haniuda K, et al. 2024. Oral bacteria induce IgA autoantibodies against a mesangial protein in IgA nephropathy model mice. Life Science Alliance7

Bogh KL, Nielsen DM, et al. 2024. Degree of hydrolysis is a poor predictor of the sensitizing capacity of wheyand casein-based hydrolysates in a Brown Norway rat model of cow's milk allergy. Food Research International181

Nechanitzky R, Ramachandran P, et al. 2024. CaSSiDI: novel single-cell Cluster Similarity Scoring and Distinction Index reveals critical functions for PirB and context-dependent Cebpb repression. Cell Death And Differentiation31:280-291

Kates M, Saibil SD. 2024. Reprogramming T-cell metabolism to enhance adoptive cell therapies. International Immunology

Chen ZY, Mortha A. 2024. INPP4B ensures that ILC1s and NK cells set up a productive home office. Journal Of Experimental Medicine221

Lien SC, Ly D, et al. 2024. Tumor reactive ?? T cells contribute to a complete response to PD-1 blockade in a Merkel cell carcinoma patient. Nature Communications15

Robbrecht D, Grob JJ, et al. 2024. Biomarker and pharmacodynamic activity of the transforming growth factor-beta (TGF?) inhibitor SAR439459 as monotherapy and in combination with cemiplimab in a phase I clinical study in patients with advanced solid tumors. Cts-clinical And Translational Science17

Varo R, Crowley VM, et al. 2024. Adjunctive rosiglitazone treatment for severe pediatric malaria: A randomize d placebo-controlle d trial in Mozambican children. International Journal Of Infectious Diseases139:34-40

Schweizer L, Bi PY, et al. 2024. NLRX1: Versatile functions of a mitochondrial NLR protein that controls mitophagy. Biomedical Journal47

Muñoz-Grajales C, Barraclough ML, et al. 2024. Serum S100A8/A9 and MMP-9 levels are elevated in systemic lupus erythematosus patients with cognitive impairment. Frontiers In Immunology14

Dunn SE, Correale J, et al. 2024. Editorial: Environmental factors in autoimmunity. Frontiers In Immunology14

Turner PJ, Eiwegger T. 2024. Improving may contain labels: A call to team up and share data. Allergy

Mukherjee T, Kumar N, et al. 2024. The NF-?B signaling system in the immunopathogenesis of inflammatory bowel disease. Science Signaling17

Schneider Y, Gauer C, et al. 2024. Distinct forebrain regions define a dichotomous astrocytic profile in multiple system atrophy. Acta Neuropathologica Communications12

Sillcox C, Gabrielli S, et al. 2024. Assessing Pediatric Cephalosporin Allergic Reactions Through Direct Graded Oral Challenges. Journal Of Allergy And Clinical Immunology-in Practice12

Day E, Galiwango RM, et al. 2024. Insertive vaginal sex is associated with altered penile immunology and enrichment of Gardnerella vaginalis in uncircumcised Ugandan men. American Journal Of Reproductive Immunology91

Whittall-Garcia LP, Naderinabi F, et al. 2024. Circulating neutrophil extracellular trap remnants as a biomarker to predict outcomes in lupus nephritis. Lupus Science & Medicine11

Tai SL, Mortha A. 2024. Neonatal monocytes suppress adult TH17 cell responses in skin. Nature Reviews Immunology24:3-3

Al Olabi R, Hendy AE, et al. 2023. The inhibitory NKR-P1B receptor regulates NK cell-mediated mammary tumor immunosurveillance in mice. Oncoimmunology12

Fernandes I, Funakoshi S, et al. 2023. Modeling cardiac fibroblast heterogeneity from human pluripotent stem cell-derived epicardial cells. Nature Communications14

Desai J, Alonso G, et al. 2023. Divarasib plus cetuximab in KRAS G12C-positive colorectal cancer: a phase 1b trial. Nature Medicine

Scipione CA, Hyduk SJ, et al. 2023. Unveiling the Hidden Landscape of Arterial Diseases at Single-Cell Resolution. Canadian Journal Of Cardiology39:1781-1794

Shah PJ, Kabuti R, et al. 2023. Childhood and adolescent factors shaping vulnerability to underage entry into sex work: a quantitative hierarchical analysis of female sex workers in Nairobi, Kenya. Bmj Open13

Bergeron J, Capo-Chichi JM, et al. 2023. The Clinical Utility of FLT3 Mutation Testing in Acute Leukemia: A Canadian Consensus. Current Oncology30:10410-10436

Kibel S, Kuehne N, et al. 2023. The Role of Adjuvant Radiotherapy for the Treatment of Resected High-Risk Stage III Cutaneous Melanoma in the Era of Modern Systemic Therapies. Cancers15

Naouar I, Rebai WK, et al. 2023. A Prospective cohort study of zoonotic cutaneous leishmaniasis in tunisia: Clinical and Immunological features and immune correlates of protection. Plos Neglected Tropical Diseases17

Ting KKY, Jongstra-Bilen J, et al. 2023. The multi-faceted role of NADPH in regulating inflammation in activated myeloid cells. Frontiers In Immunology14

Chua C, Salimzadeh L, et al. 2023. IL-2 produced by HBV-specific T cells as a biomarker of viral control and predictor of response to PD-1 therapy across clinical phases of chronic hepatitis B. Hepatology Communications7

Van JAD, Luo Y, et al. 2023. Postpartum defects in inflammatory response after gestational diabetes precede progression to type 2 diabetes: a nested case-control study within the SWIFT. Metabolism-clinical And Experimental149

Milton-Jones H, Soussi S, et al. 2023. An international RAND/UCLA expert panel to determine the optimal diagnosis and management of burn inhalation injury. Critical Care27

Ting KKY, Yu P, et al. 2023. Oxidized Low-Density Lipoprotein Accumulation Suppresses Glycolysis and Attenuates the Macrophage Inflammatory Response by Diverting Transcription from the HIF-1? to the Nrf2 Pathway. Journal Of Immunology211:1561-1577

Fisher SA, Jao JK, et al. 2023. Association of Fatty Acid Signatures with HIV Viremia in Pregnancy. Aids Research And Human Retroviruses

Liu SF, Saunders M, et al. 2023. Chemical carcinogens: implications for cancer treatment. Journal Of Clinical Investigation133

Lau SCM, Perdrizet K, et al. 2023. Programmed Cell Death Protein 1 Inhibitors and MET Targeted Therapies in NSCLC With MET Exon 14 Skipping Mutations: Efficacy and Toxicity as Sequential Therapies. Jto Clinical And Research Reports4

Last Updated March 28, 2024


See the basic research related to, and informational pamphlets about the COVID-19 pandemic from our faculty and students.


View a presentation from Professor Tania Wattsexplaining the immunology of COVID-19 as well as information relating to the newly developed vaccines.

The cover of IMMpress magazine showing a stylized phylogeny tree with the words "International Immunology" written out

IMMPress Magazine

In this issue of IMMpress, the interconnectedness of international research is visually represented in a chord diagram resembling earth. A chord diagram is commonly used to illustrate the inter-relationships between entities, with each arc bridging from one point to another to demonstrate their connection. As depicted, research does not occur in isolation; it is intricately connected to not only other research nodes, but the broader world. In a way, we are all integral parts of a larger network of effort aimed at creating a better world for everyone.

Women looking at mirror


UofTMed is an alumni magazine like no other. Bold, ambitious and lively, we dive into medicine’s most pressing topics. Read the latest issue of UofTMed magazine, with all your favourite regular departments and provocative feature articles.