Professor  |  The John David Eaton Chair in Multiple Sclerosis

Veronique Miron

PhD

Location
St. Michael's Hospital
Address
Room 413, Keenan Research Centre for Biomedical Science, 209 Victoria Street, Toronto, Ontario Canada M5B 1T8
Research Interests
Developmental Immunology, Innate Immunity
Clinical Interests
Macrophages, Multiple Sclerosis
Appointment Status
Primary
Accepting
Grad Students Must First Apply Through Department

The insulation surrounding our nerve fibres, termed myelin, is critical for healthy functioning of the central nervous system, yet is damaged in numerous neurological conditions across the lifespan, including multiple sclerosis, cerebral palsy, dementia and Alzheimer’s disease.

My lab is focused on understanding the cellular and molecular mechanisms that support myelin health and repair and how these are dysregulated with central nervous system pathology, in order to identify new therapeutic targets and strategies. We are particularly focused on the role of macrophages in regulating the development, degeneration, and regeneration of myelin, including the central nervous system resident microglia. We have identified novel processes by which microglia adopt their regenerative capacity following damage, factors they secrete that regulate myelin health, and complementary roles of other cell types in these contexts (such as monocytes and astrocytes).

We are a team of enthusiastic, friendly, and collaborative individuals, committed to creating an inclusive and supportive environment for our exciting science to flourish.