Assistant Professor  |  Assistant Professor, Institute of Biomedical Engineering

Omar Khan


St. George Campus
164 College Street, 4th Floor, Toronto, Ontario Canada M5S3G5
Research Interests
Adaptive Immunity, Autoimmunity, Cancer Immunology, Developmental Immunology, Infectious Diseases, Innate Immunity, Transplantation Immunology, Vaccines, Tissue inflammation
Appointment Status

Professor Omar F. Khan and the OFK Lab combine engineering, immunology and chemistry fundamentals to create new nanotechnologies for better patient outcomes. These technologies control and deliver nucleic acids. There are many kinds of useful nucleic acids that, if deployed correctly as nanotechnology payloads, can regulate genes in a patient’s body to achieve a therapeutic effect. These RNA molecules can silence or express genes without germline modifications and small molecule drugs. Using a multiplexing approach, many different RNA molecules are simultaneously delivered to a desired cell type to facilitate multigene control.  This method enables complex genetic studies and better disease treatments. The platform technologies developed in the OFK Lab have many application including non-traditional vaccines, the treatment of musculoskeletal diseases, cellular therapies, vascular engineering and regenerative medicine.