Trinity College in the Summer

Department of Immunology

Congrats to Dr. Pailin Chiaranunt, recent PhD Immunology alumna from Dr. Arthur Mortha's Lab within Temerty Faculty of Medicine, University of Toronto, for being one of just TWO University of Toronto recipients of the prestigious 2024 Chorafas Foundation Prize.

Dimitris N. Chorafas Foundation information & the full list of winners can be found here.

Congratulations to Dr. Veronique Miron from the Department of Immunology at the University of Toronto for being elected as a Member of the Royal Society of Canada's College of New Scholars, Artists and Scientists!

Read more about it in this U of T Article.

Congratulations to Dr. Janna Shapiro, co-supervised by Dr. Tania Watts, Immunology, and Dr. Shelly Bolotin, Dalla Lana School of Public health, for receiving the Alice Wilson Award from the Royal Society of Canada. 

Read more about it in this U of T Article.

Congratulations to Dr. Eleanor Fish for being elected as a Fellow of the Canadian Academy of Health Sciences.

Dr. Fish is a Professor and the Associate Chair of International Initiatives & Collaborations with the Department of Immunology.

Read more about it in the CAHS Article.

Congratulations to Dr. Akiko Iwasaki for receiving the 2024 Dean's Alumni - Impact Award from the Temerty Faculty of Medicine, University of Toronto.

Dr. Iwasaki is a PhD Alumna from the Department of Immunology.

Read more about it in the Temerty Faculty of Medicine, University of Toronto Article

Congratulations to Dr. Pailin Chiaranunt for being named as one of the 2024 Schmidt Science Fellows!
Dr. Chiaranunt is a PhD alumna from the Department of Immunology within the Temerty Faculty of Medicine, University of Toronto where she researched macrophages and the human microbiome under the supervision of Dr. Arthur Mortha.

More Information:
Schmidt Science Fellows - Dr. Chiaranunt Announcement 
University of Toronto Article 
The Globe & Mail Article 

Dr. Tak Mak's interview was featured on PBS on May 7, 2024.

RECENT PUBLICATIONS FROM OUR DEPARTMENT

Chung DC, Ghaedi M, et al. 2024. Characterization of innate lymphoid cell subsets infiltrating melanoma and epithelial ovarian tumors. Oncoimmunology13

Hamidzada H, Pascual-Gil S, et al. 2024. Primitive macrophages induce sarcomeric maturation and functional enhancement of developing human cardiac microtissues via efferocytic pathways. Nature Cardiovascular Research

Chow S, Lee SPN, et al. 2024. Diagnosis of systemic mastocytosis with cryptic deletion of TET2 and DNMT3A resulting from unbalanced translocation. British Journal Of Haematology

Loves R, Grunebaum E. 2024. FAS signalling pathway is crucial for CAR T cell persistence. Nature Reviews Immunology

Persaud AT, Khela J, et al. 2024. Virion-incorporated CD14 enables HIV-1 to bind LPS and initiate TLR4 signaling in immune cells. Journal Of Virology

Ting KKY. 2024. Fructose-induced metabolic reprogramming of cancer cells. Frontiers In Immunology15

Mahtani T, Sheth H, et al. 2024. The ion channel TRPV5 regulates B-cell signaling and activation. Frontiers In Immunology15

Dhume SH, Balogun K, et al. 2024. Perinatal exposure to atazanavir-based antiretroviral regimens in a mouse model leads to differential long-term motor and cognitive deficits dependent on the NRTI backbone. Frontiers In Molecular Neuroscience17

Zannikou M, Fish EN, et al. 2024. Signaling by Type I Interferons in Immune Cells: Disease Consequences. Cancers16

Bi PY, Killackey SA, et al. 2024. Cytosolic retention of HtrA2 during mitochondrial protein import stress triggers the DELE1-HRI pathway. Communications Biology7

Touahri Y, Hanna J, et al. 2024. Pten regulates endocytic trafficking of cell adhesion and Wnt signaling molecules to pattern the retina. Cell Reports43

Ting KKY. 2024. Fructose overconsumption-induced reprogramming of microglia metabolism and function. Frontiers In Immunology15

Zakrzewski JL, Suh D, et al. 2024. Tumor immunotherapy across MHC barriers using allogeneic T-cell precursors (Vol 26, pg 453, 2008). Nature Biotechnology42:674-674

Paul MS, Saibil SD, et al. 2024. Ex vivo activation of the GCN2 pathway metabolically reprograms T cells, leading to enhanced adoptive cell therapy. Cell Reports Medicine5

Lee S, Yeung KKM, et al. 2024. Tissue-resident memory T cells in protective immunity to influenza virus. Current Opinion In Virology65

Clotet-Freixas S, Zaslaver O, et al. 2024. Sex differences in kidney metabolism may reflect sex-dependent outcomes in human diabetic kidney disease. Science Translational Medicine16

Wang AA, Luessi F, et al. 2024. B cell depletion with anti-CD20 promotes neuroprotection in a BAFF-dependent manner in mice and humans. Science Translational Medicine16

Almomani O, Nnamutete J, et al. 2024. Effect of cryopreservation on CD4+T cell subsets in foreskin tissue. PLOS One19

Gorczynski R. 2024. Translation of Data from Animal Models of Cancer to Immunotherapy of Breast Cancer and Chronic Lymphocytic Leukemia. Genes15

Gommerman JL. 2024. What Jane Jacobs has taught me about neuroimmunology. Nature Immunology25:381-381

Ucciferri CC, Gower A, et al. 2024. Scoring Central Nervous System Inflammation, Demyelination, and Axon Injury in Experimental Autoimmune Encephalomyelitis. JOVE-journal Of Visualized Experiments

Robbrecht D, Grob JJ, et al. 2024. Biomarker and pharmacodynamic activity of the transforming growth factor-beta (TGF?) inhibitor SAR439459 as monotherapy and in combination with cemiplimab in a phase I clinical study in patients with advanced solid tumors. CTS-clinical And Translational Science17

Popovic A, Cao EY, et al. 2024. Commensal protist Tritrichomonas musculus exhibits a dynamic life cycle that induces extensive remodeling of the gut microbiota. ISME Journal18

Altieri A, Marshall CL, et al. 2024. Human Host Defense Peptide LL-37 Suppresses TNF?-Mediated Matrix Metalloproteinases MMP9 and MMP13 in Human Bronchial Epithelial Cells. Journal Of Innate Immunity16:203-215

Last Updated May 29, 2024

COVID-19 INFORMATION

See the basic research related to, and informational pamphlets about the COVID-19 pandemic from our faculty and students.

COVID-19, VACCINES AND HOW THEY WORK

View a presentation from Professor Tania Wattsexplaining the immunology of COVID-19 as well as information relating to the newly developed vaccines.

The cover of IMMpress magazine showing a stylized phylogeny tree with the words "International Immunology" written out

IMMPress Magazine

In this issue of IMMpress, the interconnectedness of international research is visually represented in a chord diagram resembling earth. A chord diagram is commonly used to illustrate the inter-relationships between entities, with each arc bridging from one point to another to demonstrate their connection. As depicted, research does not occur in isolation; it is intricately connected to not only other research nodes, but the broader world. In a way, we are all integral parts of a larger network of effort aimed at creating a better world for everyone.

Women looking at mirror

UofTMed 

UofTMed is an alumni magazine like no other. Bold, ambitious and lively, we dive into medicine’s most pressing topics. Read the latest issue of UofTMed magazine, with all your favourite regular departments and provocative feature articles.