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Department of Immunology

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Hearts Calendar

The Office of the Vice Dean, Research and Health Science Education (RHSE) is pleased to provide the Health Education and Research Training Series (HEARTS) calendar.

Study finds promising biomarker associated with progression and brain inflammation in MS

Headshot of Dr. Gommerman and Dr. Ramaglia

Check out this article by Temerty Medicine highlighting the recent research led by Department of Immunology Professor and Chair Jen Gommerman, and Assistant Professor Valeria Ramaglia.

Published in Nature Immunology, the study identified a promising biomarker associated with disease progression and brain inflammation in multiple sclerosis.

Study Uncovers the Role of the Gut in Sustained Immunity Against Viruses

Headshot of Dr. Gommerman and Dr. Ramaglia

Check out this article by Temerty Medicine highlighting the recent research led by Professor and Department of Immunology Chair Jen Gommerman, and postdoctoral fellow Kei Haniuda.

Published in Cell, the study shows that the gut environment enables long-lasting IgA responses, offering insights that could transform vaccine design for viral infections like influenza, SARS-CoV-2, and bird flu.

Leading innovation: Dr. Arthur Mortha

Dr. Arthur Mortha

Check out the profile on Dr. Arthur Mortha by Temerty Medicine!

Dr. Dana Philpott renewed as Canada Research Chair (Tier 1) in Microbe-Host Interactions in Intestinal Homeostasis

Headshot of Dr. Dana Philpott

Congratulations to Dr. Dana Philpott (Professor & Associate Chair, Research - Department of Immunology) on the renewal of her Canada Research Chair (Tier 1) in Microbe-Host Interactions in Intestinal Homeostasis.

Learn more about this achievement and other U of T researchers making an impact here: https://www.utoronto.ca/celebrates/41-u-t-researchers-awarded-new-or-renewed-canada-research-chairs

Blueprints of Immunity: Designing the Next Generation of Antibodies

symposium

Join us on October 31st at MSB 2172 (with registration in the David Naylor Student Commons) to discover the cutting edge of monoclonal antibody innovation. This free, one-day symposium will feature talks from local and international experts. From computational design to novel delivery platforms, this event offers deep insights, networking opportunities, and a front-row seat to the future of the field.

Who should participate? Researchers, clinicians, trainees, biotech professionals, and anyone passionate about advancing antibodies and biologics.

Register to attend: https://forms.office.com/r/i09kw5CydX

Dr. Rae Yeung appointed Scientific Director of the CIHR Institute of Musculoskeletal Health and Arthritis

Headshot of Dr. Rae Yeung

Congratulations to Dr. Rae Yeung for being appointed Scientific Director of the Canadian Institutes of Health Research (CIHR) Institute of Musculoskeletal Health and Arthritis (CIHR-IMHA) for a four-year term, effective October 1, 2025!

Learn more in the official news release from the Government of Canada here.

Dr. Bhupesh Kumar Thakur named the 2025 BD Biosciences Immunology Postdoctoral Research Award recipient

Headshot of Bhupesh
  • Congratulations to Dr. Bhupesh Kumar Thakur on being named the 2025 BD Biosciences Immunology Postdoctoral Research Award recipient!
  • The BD Biosciences Immunology Postdoctoral Research Award took place on 10 APRIL 2025.

Scientists discover a new connection between gut microbiome and inflammation through ‘happy accident’

Article

Working with PhD candidate, and now Postdoctoral Fellow, Dr. Nathaniel Winsor, they discovered an issue in mice they were using to study the interaction of the gut microbiome and colon cancer. Facing a dilemma – scrap two years of experiments or start again and dig deeper into the issue – they chose to follow their curiosity which could now change our understanding of the role of parasites in gut inflammation. Their study, a culmination of 10 years of investigation, has recently been published in Cell Host & Microbe

Study uncovers how low-carb diet drives colorectal cancer development

Article

Researchers from the University of Toronto have shown how a low-carbohydrate diet can worsen the DNA-damaging effects of some gut microbes to cause colorectal cancer.

The study, published in the journal Nature Microbiology, compared the effects of three different diets — normal, low-carb, or Western-style with high fat and high sugar — in combination with specific gut bacteria on colorectal cancer development in mice.

Dr. Arthur Mortha receives Visiting Research Professorship Award as recognition by the Canadian Association of Gastroenterologists

arthur mortha

Congratulations to Dr. Arthur Mortha for receiving the Visiting Research Professorship Award as recognition by the Canadian Association of Gastroenterologists!

Dr. Eleanor Fish receives Medal of Appreciation for COVID-19 Contributions

Headshot of Dr. Fish

Congratulations to Dr. Eleanor Fish for receiving a medal of appreciation for her exceptional contributions to Canada’s response against COVID-19 from the Chief Science Advisor of Canada - Dr. Mona Nemer and the Government of Canada!

Dr. Jen Gommerman named as one of the Distinguished Fellows of AAI - Class of 2025

Headshot of Dr. Jen Gommerman

Congratulations to Dr. Jen Gommerman (Chair, Department of Immunology) for being selected by the American Association of Immunologists (AAI) as a Distinguished Fellow of AAI —Class of 2025!

U of T study uncovers how a new gut microbe drives the gut-lung axis

FIX1

In a new study published today in the journal Cell, Artuhur Mortha, Kyle Burrows and his colleagues focused on a different category of microorganism called protozoa. These microbes are also single-celled like bacteria, but much bigger and with more complex bodies. While most known protozoa are classified as parasites, several lesser-known species can live in symbiotic relationships with their animal hosts.

Read more about the study in this article.

Dr. Jasty Singh receives Cheryl Regehr Early Career Teaching Award

Headshot of Jasty Singh

Congratulations to Dr. Jasty Singh for receiving the Cheryl Regehr Early Career Teaching Award at the Excellence in Teaching reception hosted by the University of Toronto!

Dr. Singh is the Associate Chair - Undergraduate Studies & an Associate Professor - Teaching Stream within the Department of Immunology, Temerty Faculty of Medicine, University of Toronto. 

Read more about her accomplishment and approach to teaching in this article.

Dr. Pailin Chiaranunt - 2024 Chorafas Foundation Prize Recipient

Headshot of Dr. Pailin Chiaranunt

Congrats to Dr. Pailin Chiaranunt, recent PhD Immunology alumna from Dr. Arthur Mortha's Lab within Temerty Faculty of Medicine, University of Toronto, for being one of just TWO University of Toronto recipients of the prestigious 2024 Chorafas Foundation Prize.

Dimitris N. Chorafas Foundation information & the full list of winners can be found here.

Dr. Veronique Miron - Member of the Royal Society of Canada's College of New Scholars, Artists and Scientists

Veronique Miron

Congratulations to Dr. Veronique Miron from the Department of Immunology at the University of Toronto for being elected as a Member of the Royal Society of Canada's College of New Scholars, Artists and Scientists!

Read more about it in this U of T Article.

Dr. Janna Shapiro receives Alice Wilson Award from Royal Society of Canada

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Congratulations to Dr. Janna Shapiro, co-supervised by Dr. Tania Watts, Immunology, and Dr. Shelly Bolotin, Dalla Lana School of Public health, for receiving the Alice Wilson Award from the Royal Society of Canada. 

Read more about it in this U of T Article.

RECENT PUBLICATIONS FROM OUR DEPARTMENT

Hickey JM, Sharma N, et al. 2025. PfCSP-ferritin nanoparticle malaria vaccine antigen formulated with aluminum-salt and CpG 1018� adjuvants: Preformulation characterization, antigen-adjuvant interactions, and mouse immunogenicity studies. Human Vaccines & Immunotherapeutics21

Alban J, Bowen RC, et al. 2025. Metastatic Uveal Melanoma Surveillance: A Delphi Panel Consensus. Cancers18

Nagy NA, Schnoegl D, et al. 2025. Sequence of Immunological Events During IgE-Mediated Allergic Reactions to Food. Allergy

Pollock J, Kung'u M, et al. 2025. Forced vaginal sex and genital immune correlates of HIV risk: a prospective study of female sex workers in Kenya. Bmj Global Health10

Li MX, Brito GC, et al. 2025. High-content imaging of primary chronic lymphocytic leukemia cells predicts patient cohorts with distinct cellular drug responses. Iscience28

Gimenez-Arnau AM, Maurer M, et al. 2025. Long-Term Efficacy and Safety of Ligelizumab as Re-Treatment in Patients With Chronic Spontaneous Urticaria. Allergy

Ghazale H, Pazos MP, et al. 2025. MicroRNA-mediated neuronal detargeting alters astrocyte cell fate conversion trajectories in vivo. Communications Biology8

Perfetto SE, Ruthirakuhan M, et al. 2025. Type 2 Diabetes Mellitus, Cognitive Performance, and Incident Dementia; Identifying Mediating Pathways and Biomarkers From the Plasma Proteome. Journal Of Neurochemistry169

Michael AW, Sussman G. 2025. Isolated goat and sheep milk allergy in an adult in the absence of bovine sensitization. Allergy Asthma And Clinical Immunology22

Tai SL, Wong F, et al. 2025. Group 3 innate lymphoid cell-derived CSF2 tunes homeostasis of tissue macrophages and neutrophils. Mucosal Immunology18:1450-1461

Upton JEM, Li CH, et al. 2025. Safety and Efficacy of Very Low-Dose Multi-Nut Oral Immunotherapy in Children. Clinical And Translational Allergy15

Sato T, Butler MO, et al. 2025. Incidence and Management of Adverse Events Associated with Tebentafusp Treatment in Metastatic Uveal Melanoma: Pooled Safety Analysis of 410 Patients. Clinical Cancer Research31:5027-5036

Zschocke A, Eiwegger T. 2025. IgE-mediated Food Allergies in Childhood: Diagnosis, Management, and New Treatment Options-Part 2. Paediatrie Und Paedologie

Du YJ, Guo JC, et al. 2025. Eating away at food allergy. Pediatric Allergy And Immunology36

Haniuda K, Edner NM, et al. 2025. Mucosal viral infection elicits long-lived IgA responses via type 1 follicular helper T cells. Cell188

Nahum A, Sharfe N, et al. 2025. Autosomal-dominant Roquin-1 immunodeficiency and hyperinflammation. Journal Of Allergy And Clinical Immunology156

Lee E, Picard M. 2025. Diagnosis and management of mast cell activation syndrome (MCAS) in Canada: a practical approach. Allergy Asthma And Clinical Immunology21

Nguyen AA, Fisher L, et al. 2025. Sequential lymphotoxin-? receptor and retinoic acid receptor signals regulate cDC2 fate. Nature Immunology26

Zschocke A, Eiwegger T. 2025. IgE-mediated Food Allergies in Childhood: Diagnosis, Management, and New Treatment Approaches-Part 3. Paediatrie Und Paedologie

Masopust D, Awasthi A, et al. 2025. Guidelines for T cell nomenclature. Nature Reviews Immunology

Liu FF, Khan KM, et al. 2025. Time to fund exercise programmes for cancer survivors: the evidence is mounting. British Journal Of Sports Medicine

Del Zompo F, Crouchet E, et al. 2025. Claudin-1 is a mediator and therapeutic target in primary sclerosing cholangitis. Journal Of Hepatology83

Muthuraman K, Jackman M, et al. 2025. Human antibody targeting of coronavirus spike S2 subunit is associated with protection mediated by Fc effector functions. Journal Of Virology99

Bekkering ET, Yoo R, et al. 2025. Cryo-EM structure of endogenous Pfs230:Pfs48/45 complex with six antibodies reveals mechanisms of malaria transmission-blocking activity. Immunity58:2899-2916

Zahoor MA, Fadlelmawla N, et al. 2025. Development of a CRE/CREB-driven HBx responsive HBV cell culture reporter system for antiviral drug evaluation. Jhep Reports7

Muñoz-Grajales C, Ucciferri CC, et al. 2025. IgG Sialylation Distinguish Asymptomatic From Symptomatic Antinuclear Antibody-Positive Individuals. Arthritis & Rheumatology

Xie QY, Danska JS. 2025. Large-scale microbiome data initiatives call for diversity. Trends In Microbiology33:1144-1145

Last Updated January 23, 2026

COVID-19 INFORMATION

See the basic research related to, and informational pamphlets about the COVID-19 pandemic from our faculty and students.

COVID-19, VACCINES AND HOW THEY WORK

View a presentation from Professor Tania Wattsexplaining the immunology of COVID-19 as well as information relating to the newly developed vaccines.

Magazine cover with various artistic drawings and the words "The Art of Science" written

IMMPress Magazine

While art and science are often thought to belong within the opposing realms of creativity and logic, both are at their core characterised by curiosity, exploration, and the spirit of innovation. It cannot be coincidence, after all, that some of the most renowned scientists in history were also great artists — and vice versa. In this issue of IMMpress Magazine, we seek to bring this connection into the light.

A magazine cover of a balloon with a face painted on it and a bandage on the forehead

UofTMed 

UofTMed is an alumni magazine like no other. Bold, ambitious and lively, we dive into medicine’s most pressing topics. Read the latest issue of UofTMed magazine, with all your favourite regular departments and provocative feature articles.